Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Medically reviewed by Sanjai Sinha, MD. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Their medical staff can help you set up another time to receive your Injectafer dose. Pain, swelling, or redness at the injection site may occur. 2. Here we look at how Injectafer and Feraheme are alike and different. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. 2005 - 2023 WebMD LLC. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. These are not all the side effects that may occur; contact your healthcare provider if you have questions. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. There may be drug take-back programs in your area. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. People in the study received treatment with either Injectafer or Venofer. Others last much longer (even a lifetime), which can be quite traumatizing to people. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Learn about uses, cost, how it works, and more. In the US - Call your doctor for medical advice about side effects. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. WebMD does not provide medical advice, diagnosis or treatment. Consult the product instructions and your pharmacist for storage details. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Most of these side effects may go away within a few days or a couple of weeks. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Can poor sleep impact your weight loss goals? Its responsible for carrying oxygen throughout your body. Best food forward: Are algae the future of sustainable nutrition? Its not known whether its safe to breastfeed while youre taking Injectafer. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Injectafer can cause mild or serious side effects. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Injectafer contains the active drug ferric carboxymaltose. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. pain in the arms or legs. With IV infusion, the drug is given as a slow drip into your vein over a period of time. These nutrients include iron, vitamin B12, and folate. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Any long-term side effects/dangers from iron infusions? Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. intense abdominal pain. Details. With IDA, you have low hemoglobin levels. We comply with the HONcode standard for trustworthy health information. Health careproviderscan provide information on how longside effectslast by checking amedication guide. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Your doctor will be able to see how Venofer is working by reviewing your blood tests. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. (A class of medications describes a group of drugs that work in the same way.). 3 0 obj If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. However, side effects at the 150 mg dose may indicate that you might not . This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. This can be very helpful in . With slow IV injection, the drug is given as a single, slow injection into your vein. Always review your medical history with the treatingphysician. Venofer pregnancy and breastfeeding warnings. You may need extra iron because of blood loss during kidney dialysis. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Terminal half-life ranges from 7 to 12 hours. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Many patients with kidney disease cannot get enough iron from food and require injections. <> Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. But its only approved for use in people with CKD who may or may not need dialysis. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Depending on your doctors instructions and Do not flush medications down the toilet or pour them into a drain unless instructed to do so. WebMD provides common contraindications for Venofer Vial. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. A shortage of iron can cause health problems. Its not known if Injectafer is safe to use during pregnancy. And these two doses need to be separated by at least 7 days. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Ask your doctor or healthcare provider if Venofer is the right choice for you. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Copyright 1996-2023 Cerner Multum, Inc. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. In clinical trials,. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Then your body uses that iron to make hemoglobin and RBCs. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. reactions at the site of the injection. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Also tell them about any vitamins, herbs, and supplements you use. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. endobj Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. They can tell you about other medications that may work well for you. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. stream This may be helped by giving the medication more slowly or at a lower dose. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. This hormone is made by your kidneys. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Patients with celiac disease (gluten intolerance). Talk to your pharmacist for more details. The drug helps increase your hemoglobin level back to a value thats within the normal range. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. These side effects can range from being mild to severe. With this condition, you also have a low hemoglobin level. It belongs to a class of medications called iron replacement products. (See also Notes section.). Venofer may cause significant hypotension (decreased blood pressure). * Sex and gender exist on spectrums. Does Venofer Vial interact with other medications? The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. Generics tend to cost less than brand-name drugs. And this can lead to anemia, including IDA. Remember that it is best to get your vitamins and minerals from food whenever possible. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. You may report side effects to the FDA at 1-800-332-1088. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Precautions. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Theseside effectscan range from being mild tosevere. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Dizziness. You will be watched closely by your doctor for 30 minutes after each dose. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Theseside effectsmay last as long as they are undercancer treatment. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Its not known how often people taking a treatment other than Injectafer had diarrhea. The following information describes dosages that are commonly used or recommended. For some people, it may be OK to continue taking a multivitamin that contains iron. During Injectafer treatment, your doctor will likely order blood tests. In one study, people were given either Injectafer or an iron replacement drug called Venofer. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Before using, check this product visually for particles or discoloration. It depends. There are currently no generic forms of either drug. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Together, you and your doctor can develop a treatment plan thats best for you. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. This survey is being conducted by the WebMD marketing sciences department. The benefit of treating your condition during pregnancy may outweigh any risks. In Canada - Call your doctor for medical advice about side effects. For more information about Injectafers approved uses, see the section Injectafer uses below. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. You can also write a reminder on your calendar. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Or your doctor may recommend that you change your eating habits to include more iron in your diet. It can be given as a slow injection over 2 to 5 minutes or as an infusion. For example: Say you weigh 105 pounds (about 48 kilograms). However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. 2023 Medicine.com All rights reserved. But for other people, doing so could lead to having too much iron in their body. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. But you likely wont feel the drug working inside of you. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. This medication is given by injection into a vein as directed by your doctor. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Injectafer is a brand-name prescription drug. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Theyll recommend how to manage your condition. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. But if they become more severe or dont go away, talk with your doctor or pharmacist. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. If you notice any changes to your normal blood pressure, call your doctor right away. The following information is provided for clinicians and other healthcare professionals. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Venofer treatment may be repeated if iron deficiency reoccurs. Most people will metabolize medication by half every time it circulates the body. 1 0 obj If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Venofer® (iron sucrose injection, USP) is available by prescription only. But keep in mind that in this study, delayed allergic reaction only occurred in one person. 5 0 obj Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. I had my first infusion of 1gm 10 days ago. Here are answers to some frequently asked questions about Injectafer. Its possible to get rid of or reduce the severity ofside effects. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Dizziness. However, many people have no side effects or only have minor side effects. Theyll do this by checking certain blood tests. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Side effects are uncomfortable reactions to medications or drugs. Its not known how common delayed allergic reaction might be in other people using Injectafer. HRT, like other medications, does have some side effects and these are thought to be quite common. Things to remember when you fill your prescription. If you think there has been an overdose, call your poison control center or get medical care right away. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. ByDr. Below are examples of these side effects. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. US residents can call their local poison control center at 1-800-222-1222. Iron infusions are given directly into a vein. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. It may also cause nervousness, restlessness, and difficulty sleeping in some people. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. How long does iron infusion stay in your system? And this could lead to weight gain, if they increase their food intake. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Effectiveness of Injectafer compared with iron thats taken by mouth. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Instead, youll start by receiving just one treatment course of Injectafer. You will need to talk about the benefits and risks to you and the baby. Some drugs may have another patient information leaflet. Injectafer and Feraheme are both brand-name drugs. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Why is the range so wide? While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. We cancelled my 5th because of the reaction. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. muscle pain. % <> There are currently no generic forms of either drug. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. You should not receive Venofer if you have known allergies to iron sucrose. Phosphorus also helps your nerves function properly. Phosphorus is an electrolyte that your body needs in order to make energy.

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